Your guide to the Enneking system which helps your surgeon decide about treatment for cancer that starts in your bone (primary bone cancer). A System for the Surgical Staging of. Musculoskeletal Sarcoma. WILLIAM. F. ENNEKING,. M.D.,* SUZANNE. S. SPANIER,. M.D.,** AND. MARK A. GOODMAN, . Based on a combination of histologic grade (G), anatomic site (T), and presence or absence of distant metastasis (M) Grade G0 = benign G1 = low grade.

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Each lesion ultimately is assessed on histologic features; however, some tumors are high grade by definition, such as a dedifferentiated chondrosarcoma sraging 3 ]. Anatomic compartments have inherent barriers to tumor spread, including fascial planes and bone structures.

Enneking staging system | Bone cancer | Cancer Research UK

It can also recur in another part of the body, which is called metastatic bone cancer. It denotes abnormal proliferation of cells. We will reply by email or phone if you leave us your details.

Tumors which are responsive to chemotherapy and may be treated with aggressive resection. Growth includes the processes [Modeling is also part of bone growth] that causes increase length and girth before the closure of to epiphyseal plate closure [There is gain in length after epiphyseal plate closure].

It consists of three categories: Lesions originating in the skull also behave differently and thus cannot be staged or classified using this system. Those that are not responsive to adjuvant therapy should be treated with palliative resection. National Center for Biotechnology InformationU.

Clin Orthop Relat Res. Stage 2B The cancer is high grade and has grown though the bone wall into other nearby structures. Doctors may use the simple staging system or the Enneking staging system. L6 – years in practice. Neoplasm is an abnormal mass of tissue as a result of neoplasia.



This is called an intracompartmental bone cancer. The patient feels his current pain may be related to his previous injury.

It is called an extracompartmental bone cancer. What is the likely diagnosis? Recurrent bone cancer Recurrent bone cancer means that the cancer has come back after it has been treated. Get more on Musculoskeletal Health in your inbox Subscribe to our Newsletter and get updates delivered to your email inbox.

This website is an effort to educate and support people and medical personnel on orthopedic issues and musculoskeletal health. Published online Mar Staging childhood bone cancer Staging is a way of describing or classifying a cancer based on the extent of the cancer, or where it is in the body. Prognosis of bone cancer depends on the following variables overall stage of disease incorporates all of the below presence of metastasis skip discontinous lesions within the same bone histologic grade tumor size The are two staging systems that are commonly used: Limitations The Enneking surgical staging system is based on the natural evolution of mesenchymal tumors and thus is not applicable to tumors originating in either the marrow or reticuloendothelial system.

In the Enneking staging system, a neoplasm is classified as either low G1 or high G2 grade.

Joints are also compartments with their surgical boundaries being the articular cartilage and the joint capsule. But the cancer has not grown through the bone wall or spread to any other part of the body. enneiing

Enneking Staging System and TGNM Staging System for Musculoskeletal Tumors

Bone cancer Stages and grades. As defined by the Xtaging Union Against Cancer, the objectives of cancer staging are 1 to aid in planning the course of treatment, 2 to provide insight into the prognosis, 3 to assist in evaluating the results of treatment, 4 to facilitate effective interinstitutional communication, and 5 to contribute to continuing investigation of human malignancies [ 7 ]. Radiologic and pathologic analysis of solitary bone lesions.


This means the cancer has grown out of the area compartment of the bone in which it started. Purpose An ideal staging system should be practical, reproducible, and of prognostic significance.

Staging is a way of describing or classifying a cancer based on the extent of the cancer, or where it is in the body. Thus local extent determines the approach for the surgical procedure and feasibility for desired surgical margins.

Well-demarcated borders are indicative of latent lesions whereas indistinct borders result from permeation into host bone and a more aggressive lesion [ 11 ]. Please review our privacy policy.

Bone Tumor Staging Systems – Pathology – Orthobullets

Difficulty in using the system was reported in 5. Articulation with surgical procedure is limited when compared with the Enneking staging system because of lack of consideration to anatomic planes and compartments. A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma.

Stage 3 The cancer is either inside the bone or grown stagiing the bone into nearby structures.