The Milan criteria are a generally accepted set of criteria used to assess suitability in patients for liver transplantation with cirrhosis and hepatocellular carcinoma. Avaliação do tratamento dos nódulos do hepatocarcinoma nos pacientes em lista entre pacientes incluídos no Critério de Milão ou ao downstaging (p= 0,). .. Yan L. Downstaging advanced hepatocellular carcinoma to the Milan criteria. Catorze diferentes critérios foram encontrados e descritos em detalhes. The keywords used were hepatocellular carcinoma, liver transplantation, expanded.

Author: Vushakar Vukus
Country: Nicaragua
Language: English (Spanish)
Genre: Sex
Published (Last): 6 May 2004
Pages: 420
PDF File Size: 13.32 Mb
ePub File Size: 12.4 Mb
ISBN: 283-1-69761-956-2
Downloads: 64367
Price: Free* [*Free Regsitration Required]
Uploader: Vudolkree

Following this study, several other studies demonstrated that the up-to-seven criteria could be useful as a model for evaluating potential candidates for liver transplantation to treat HCC[ 12 – 15 ]. Some have advocated for the use of expanded guidelines for liver transplantation in the setting of HCC.

In the 71 cases who were diagnosed with macrovascular invasion, 54 Peer review This is an interesting study comparing liver transplant outcomes in 3 groups of patients with different stage of HCC. European Association for the Study of the Liver.

Does it really criteios InYao et al. By using this site, you agree to the Terms of Use and Privacy Policy.

There was a problem providing the content you requested

Radiological and pathological assessment of hepatocellular carcinoma response to radiofrequency. Hepatobiliary Pancreat Dis Int. Orthotopic liver transplantation is an excellent treatment approach for hepatocellular carcinoma in well-selected candidates. Effective management of early HCC includes resection, radiofrequency ablation and liver transplantation LT.

In the present study, 71 patients The patient survival rate and tumor recurrence-free rates from 1 to 5-years were shown in Table 1.


This search resulted in a total of 39 studies. However, this bias was assumed to have no impact on our hepatocadcinoma, as the results of another of our studies indicated that there were no significant differences in postoperative complications, tumor recurrence rate, survival rate, and HBV recurrence between deceased donor liver transplant DDLT and live donor liver transplantation LDLT patients[ 22 ].

Analysis of long-term outcomes of liver transplantations over two decades: Over six years, HCC patients underwent LT at our transplantation center, and all of them were followed up for at least 5 years.

Undertreatment of elderly patients with non-small-cell lung cancer. Survival and tumor recurrence.

J Cancer Res Clin Oncol ; Anal sphincterotomy Anorectal manometry Lateral internal sphincterotomy Rubber band ligation Transanal hemorrhoidal dearterialization. Optimal treatment strategy for elderly patients with hepatocellular carcinoma.

Percutaneous ethanol injection before liver transplantation in the hepatocellular carcinoma. Criteria for critwrios transplantation for HCC: Research frontiers Although the up-to-seven criteria have been analyzed all over the world, they have not been as widely accepted as the Milan criteria, even 4 years after their conception. crterios

Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma. N Engl J Med.

Up-to-seven criteria for hepatocellular carcinoma liver transplantation: A single center analysis

Liver transplantation outcomes in 1, hepatocellular carcinoma patients: Then, we compared long-term survival and tumor recurrence of these three groups.

The length of follow-up for all the patients in our study was at least 5 years, and no significant differences were observed among the groups. Epub ahead of print. Five year’s experience in cases. Stringent inclusion criteria have been adopted to ensure tumor free survival after LT.


Our aim is to study the current situation of these several EMC proposed in order to clarify both this debate through a critical analysis of available data and addressed discussion of further parameters beyond number and size of tumors, focusing on patient survival rate and tumor recurrence free rate from 1 to 5-years after OLT. Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: Indeed, as observed in previous reports, we found that tumors that exceeded the MC criteria were more likely to have evidence of vascular invasion in the explants 21, The MC is considered the gold standard for selection of the best HCC candidates for OLT after numerous external validations of the seminal proposed Expansion of tumor criteria for transplantation risks including patients with higher-grade tumors or microvascular invasion who might have a higher risk of recurrence.

Liver organ allocation for hepatocellular carcinoma: Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. All of these patients were diagnosed with HCC based on pre-operative imaging studies, and the diagnoses were confirmed by pathology.

Chronic liver disease in the extremely elderly of 80 years or more: Adult living donor liver transplantation for patients with hepatocellular carcinoma: The surgical approach to HCC: