Fournier’s gangrene, an obliterative endarteritis of the subcutaneous arteries resulting in gangrene of the overlying skin, is a rare but severe infective necrotizing. Profile of patients with Fournier’s gangrene and their clinical evolution. Perfil dos pacientes com gangrena de Fournier e sua evolução clínica. DJONEY RAFAEL. La gangrena de Fournier es una infección grave de la zona genital de los ciertas afecciones corren un mayor riesgo de llegar a tener gangrena de Fournier.

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The management of FG is underscored by fisiopatoloiga main principles: The diagnosis is often made clinically, although radiography can be helpful when the diagnosis or the extent of the disease is difficult to discern.

The negative pressure in NPWT leads to an increased blood supply and thus encourages migration of inflammatory cells into the wound region. Can Urol Assoc J 7: Other organisms like Bacteroides inhibit the phagocytosis of aerobic bacteria, aiding in further spread of the infection [ Morua et al.

Fournisr a retrospective review of 41 patients presenting with FG, Chen and colleagues found that scrotal advancement flaps provided good skin quality and cosmesis in small to medium sized scrotal defects. The aim of this study was to analyze dd epidemiological and clinical characteristics of Fournier gangrene along with the variables that influence disease course and mortality in patients treated in our department. The polymicrobial nature of FG with contributions by both aerobic and anaerobic bacteria fisiopatoogia necessary to create the production of various fisopatologia and enzymes like collagenase, heparinase, hyaluronidase, streptokinase and streptodornase, which promote rapid multiplication and spread of infection.

SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. Moreover, the flap was found to be less bulky than a gracilis flap with minimal donor site morbidity [ Chen et al. Treatment of FG entails treating sepsis, stabilizing medical parameters and urgent surgical debridement.

Chan and collages state that implantation of the exposed testicle into an adjacent subcutaneous thigh flap can provide a shorter hospital stay and reduce recovery time. Magnetic resonance imaging MRI offers an important diagnostic adjunct in the management of FG as it is more useful than conventional radiography and US for specifying range of infection.

If you are a member of the AEDV: The relatively high incidence of FG in patients with diabetes has been attributed to their small vessel disease, defective phagocytosis, diabetic neuropathy and immunosuppression, all of which can be exacerbated by poor hygiene when present [ Vick and Carson, ]. The mean hospital stay was Meanwhile, patients with large and deep perineal defects often needed a myocutaneous or fasciocutaneous flap to eliminate dead space.


FG is a rare necrotizing fasciitis of the perineal, genital and perianal region with an aggressive clinical course. This imaging modality is also useful in differentiating FG from inguinoscrotal hernias.

Contemporary diagnosis and management of Fournier’s gangrene

However, split-thickness skin grafts STSGs are preferred over FTSGs for trauma, avulsions, burns and hidradenitis suppurativa because of gangrenq take in these contaminated wounds.

In this case review, all four patients reported satisfaction with their cosmetic and functional results. Statistically significant differences were observed between the age of surviving patients and that of patients who died Maguina and colleagues reported their experience with meshed STSGs in four patients who presented with FG with subsequent radical debridement and complete or near complete loss of the scrotum.

As a result of these defects, ensuing exposure of the testicles in the male patient presents a substantial challenge for reconstruction.

Alternatively, clindamycin and chloramphenicol can be substituted empirically to facilitate coverage of gram-positive cocci and anaerobes until culture results return gisiopatologia Martinez-Rodriguez et al. Post Grad Med J Predisposing factors Primarily an infective condition, FG has several predisposing factors and theoretically, any condition that decreases the host immunity may predispose a person to the development of FG.

Overall, the authors analyzed cases of FG at a total of hospitals. Report of 45 cases.

Plast Reconstr Surg Continuing navigation will be considered as acceptance of this use. Subjects of both genders and all ages may be affected [ Sorensen et al. The diagnosis of FG is primarily clinical, and in most cases imaging is neither necessary nor desirable. Actas Urol Gxngrena A significant weakness of radiography in the diagnosis and evaluation of FG is the lack of detection of deep fascial gas [ Wysoki et al.

Using a weighted point system of multiple laboratory markers, the Laboratory Risk Indicator for Necrotizing Fasciitis LRINEC score is often used to stratify patients into low, moderate or high risk for necrotizing soft tissue infections [ Wong et al. The ve goal of reconstruction in patients who have undergone genital skin loss due to necrotizing fasciitis is simple and efficient coverage.


Pathogenesis and organisms involved The predisposing and etiologic factors of FG provide a favorable environment for the infection by decreasing the host immunity and allowing a portal of entry for the microorganism into the perineum.

ANZ J Fisippatologia Tahmaz and colleagues found the efficacy of unprocessed honey to be similar in a vangrena review of 33 patients treated with topical honey versus radical surgical debridement [ Tahmaz et al. In the year has been indexed in the Medlinedatabase, and has become a vehicle for expressing the most current Spanish medicine and modern.

Topical therapy After initial radical debridement, open wounds are generally managed with sterile dressings or negative-pressure wound therapy.

Gangrena de Fournier | Cigna

Salvaging the testes is usually achieved by using techniques such as thigh pouches, skin grafts and use of fasciocutaneous or musculocutaneous flaps [ Corman et al.

Interestingly, patients treated at teaching hospitals had longer length of stay, greater hospital charges and a higher case fatality rate secondary to more acutely ill patients. In 74 patients presenting with FG at an Egyptian medical center, adequate urinary diversion was accomplished with the use of a urethral Foley catheter in all but one patient who had experienced a urethral injury. Overall, US is considered superior to conventional radiography as soft tissue air is more obvious and scrotal contents along with Doppler blood flow can be examined.

Contemporary diagnosis and management of Fournier’s gangrene

The diagnosis of FG is primarily based on clinical findings of fluctuance, crepitus, localized tenderness and wounds of the genitalia and perineum. However, they are still clinically effective and successfully used in the management of large wounds [ Czymek et al.

It is imperative that the antibiotic regimen chosen is effective against staphylococcal, streptococcal and gram-negative bacteria, coliforms, Pseudomonas, Bacteroides and Clostridium [ Mallikarjuna et al. Overall, the data in the study revealed that hospitals where more patients with FG are treated had lower mortality rates, supporting the need to regionalize care for patients with this disease [ Sorensen et al.

Go to the members area of the website of the AEDV, https: Based on analysis of individual comorbid conditions, only ischemic heart disease displayed a fournjer significant association with mortality due to Fournier gangrene; ischemic heart disease was also associated with longer hospital stay.