Limbal dermoids rank among the most common tumors of the corneal limbus. They are ocular choristomas and can occur in a variety of sizes. Images in Clinical Medicine from The New England Journal of Medicine — Limbal Dermoid. Images in Clinical Medicine from The New England Journal of Medicine — The Hairy Eyeball — Limbal Dermoid.

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The appropriate time of intervention and the best surgical technique for removal of the pediatric limbal dermoids are subject to discussion.

ddermoid Amniotic membrane transplantation in ophthalmology fresh v preserved tissue Br J Ophthalmol. No pallor or edema of either disc. Conservative management by observation may limball be a suitable option for such lesions. He had mild neonatal jaundice that did not require treatment and was improving.

Some affected individuals may have congenital heart defects, renal defects hypoplasia or agenesisor central nervous sytem CNS malformations intracranial lipomas, hydrocephalus, cranial nerve dysgenesis and mental retardation.

Fibrin-glue assisted multilayered amniotic membrane transplantation in surgical management of pediatric corneal limbal dermoid: The case we present here is certainly a more mild variation of the Goldenhar condition.

Goldenhar Syndrome (Oculo-Auriculo-Vertebral Spectrum):

Outcome of lamellar keratoplasty for limbal dermoids in children. Goldenhar syndrome also known as oculo-auriculo-vertebral spectrum or hemifacial microsmia is a developmental malformation of the first and second branchial arches.

Footnotes Disclosure The author reports no conflicts of interest in this work. Limbal stem cell deficiency with a pseudopterygium developed in four eyes, one treated with bare-sclera excision and the others with amniotic membrane transplantation. Ratio of patients without pseudopterygium in the groups with or without MMC.


Opacification of part of the graft was seen in When any of the above conditions or combination of conditions is noted, surgery should be considered and thoroughly discussed with the parents, including the potential risk of scarring, the requirement for ongoing treatment of amblyopia after surgery, need for spectacle or contact lens wear, possible repeat surgery, and loss of vision.

Visual acuity remained unchanged. However, if adherence with spectacle wear is good in the setting of large, regular, and oblique astigmatism, and adequate follow-up for clinical treatment of amblyopia is possible, surgeons may opt to defer surgical intervention.

Cambridge University Press; This article has been cited by other articles in PMC. They concluded FG-assisted augmented AMT was easily performed for repairing large corneal perforations.

Management of pediatric corneal limbal dermoids

All surgeries were performed by the same surgeon. Am J Med Genet A. Amercian Academy of Opthalmology; Lazzaro Drmoid, Coe R. Grade II limbal dermoids are of larger size and extend into the corneal stroma down to Descemet’s membrane.

The transplantation of amniotic membrane following removal of a limbal dermoid cannot prevent the occurrence of a pseudopterygium.

The size of the lesion, ideally captured and measured by digital photography, visual acuity, stereo acuity, cycloplegic refraction, and gonioscopy, need to be addressed, whenever possible. The limbal dermoid on the left limbaal has not changed in size, does not threaten the visual axis and derrmoid not inhibit closure of the li,bal see Figure 2B and 3.

Pre and postoperative photographical data were available for all patients Figures 1a and b, and 2a and b. The inhibition of fibroblast growth by Mitomycin C is also reported in the treatment of a primary pterygium, a recurrent pterygium, and in filtering bleb surgery. Grade III limbal dermoids, the least common of all the presenting dermoids, are large lesions covering the whole cornea and extending through the histological structures between the anterior surface of the eyeball and the pigmented epithelium of the iris Figure 3.


Panton RW, Sugar J. Of note, a subgroup of these limbap, ie, sebaceous nevus, is known to undergo malignant transformation. The data of 12 consecutive patients 14 eyes eermoid, who underwent monocentric surgery of a limbal demoid in the past 9 years, were retrospectively analyzed for intra and postoperative complications.

Limbal cells cultivated on denuded amniotic membrane formed a nicely stratified layer that adhered well to the underlying amniotic membrane. Left eye slit lamp view shows the elevated, fatty appearance of this limbal dermoid.

Goldenhar’s syndrome associated with multiple congenital abnormalites.

All patients had been treated consecutively in the past 9 years. These steps are necessary in order to plan for the appropriate surgical approach.

Management of pediatric corneal limbal dermoids

The mean age at the time of the surgery was 4. Sutures were removed li,bal 2 weeks. Three patients had a diagnosis of Goldenhar syndrome.

The method of choice to treat a limbal dermoid is surgical excision. Not a single limgal treated with Mitomycin C developed a pseudopterygium. Males are more affected than females in a 2: Dermoid excision and lamellar keratoplasty was performed in 48 eyes, simple excision was performed in two eyes, and a penetrating graft was performed in one eye.